6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one.

ABSTRACT: The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the mol-ecule is generally planar within 0.037?(3)?Å; the eight-membered ring exhibits an inter-mediate conformation between the chair and boat forms as it is typical for cyclo-octene rings. An ethyl-ene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910?(7):0.090?(7). In the crystal, the H atoms of the aromatic rings form weak C-H?O and C-H?N hydrogen bonds. One C-H?O hydrogen bond leads to the formation of a one-dimensional chain. Another C-H?O and a C-H?N bond link these chains, generating a three-dimensional network.

SUBMITTER: Okmanov RY 

PROVIDER: S-EPMC2977403 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature