Ontology highlight
ABSTRACT:
SUBMITTER: Karayiorgou M
PROVIDER: S-EPMC2977984 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Karayiorgou Maria M Simon Tony J TJ Gogos Joseph A JA
Nature reviews. Neuroscience 20100601 6
Recent studies are beginning to paint a clear and consistent picture of the impairments in psychological and cognitive competencies that are associated with microdeletions in chromosome 22q11.2. These studies have highlighted a strong link between this genetic lesion and schizophrenia. Parallel studies in humans and animal models are starting to uncover the complex genetic and neural substrates altered by the microdeletion. In addition to offering a deeper understanding of the effects of this ge ...[more]