Ontology highlight
ABSTRACT:
SUBMITTER: Ju YS
PROVIDER: S-EPMC2978381 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Ju Young Seok YS Hong Dongwan D Kim Sheehyun S Park Sung-Soo SS Kim Sujung S Lee Seungbok S Park Hansoo H Kim Jong-Il JI Seo Jeong-Sun JS
Nucleic acids research 20100827 20
Comparative genomic hybridization (CGH) microarrays have been used to determine copy number variations (CNVs) and their effects on complex diseases. Detection of absolute CNVs independent of genomic variants of an arbitrary reference sample has been a critical issue in CGH array experiments. Whole genome analysis using massively parallel sequencing with multiple ultra-high resolution CGH arrays provides an opportunity to catalog highly accurate genomic variants of the reference DNA (NA10851). Us ...[more]