Ontology highlight
ABSTRACT:
SUBMITTER: Ghochani M
PROVIDER: S-EPMC2980740 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Ghochani M M Nulton J D JD Salamon P P Frey T G TG Rabinovitch A A Baljon A R C AR
Biophysical journal 20101101 10
We present a model from which the observed morphology of the inner mitochondrial membrane can be inferred as minimizing the system's free energy. In addition to the usual energetic terms for bending, surface area, and pressure difference, our free energy includes terms for tension that we hypothesize to be exerted by proteins and for an entropic contribution due to many dimensions worth of shapes available at a given energy. We also present measurements of the structural features of mitochondria ...[more]