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4-(3,3-Dimethyl-perhydro-1,3-oxa-zolo[3,4-a]pyridin-1-yl)-2,8-bis-(tri-fluoro-meth-yl)quinoline.

ABSTRACT: An L-shaped conformation is found in the title mol-ecule, C(20)H(20)F(6)N(2)O, the C-C-C-C torsion angle linking the two fused-ring systems being -92.80?(19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579?(2)?Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra-molecular chains are found in the crystal structure that are sustained by C-H?? and ?-? [3.6089?(10)?Å] inter-actions.

SUBMITTER: Wardell JL

PROVIDER: S-EPMC2983630 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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4-(3,3-Dimethyl-perhydro-1,3-oxa-zolo[3,4-a]pyridin-1-yl)-2,8-bis-(tri-fluoro-meth-yl)quinoline.

Wardell James L JL Wardell Solange M S V SM Tiekink Edward R T ER

Acta crystallographica. Section E, Structure reports online 20100227 Pt 3

An L-shaped conformation is found in the title mol-ecule, C(20)H(20)F(6)N(2)O, the C-C-C-C torsion angle linking the two fused-ring systems being -92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra-molecular chains are found in the crystal structure that are sustained by C-H⋯π and π-π [3.6089 (10) Å] inter-actions. ...[more]

PMID: 21580439

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