Ontology highlight
ABSTRACT:
SUBMITTER: Goncalves RS
PROVIDER: S-EPMC3151884 | biostudies-other | 2011 Jul
REPOSITORIES: biostudies-other
Acta crystallographica. Section E, Structure reports online 20110618 Pt 7
In the title mefloquine-oxazolidine derivative, C(24)H(20)F(6)N(2)O(2), the oxazoline ring adopts an envelope conformation (the flap atom is N) and the piperidine ring has a chair conformation. The oxazoline and benzene residues lie away from the C(6) ring of the quinoline group and, to a first approximation, to one side of the plane through the ten atoms (r.m.s. deviation = 0.025 Å). An intra-molecular O-H⋯N(piperidine) hydrogen bond is present. The crystal packing features C-H⋯O, C-H⋯F and C-H ...[more]