Ontology highlight
ABSTRACT:
SUBMITTER: Scott MS
PROVIDER: S-EPMC2995072 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Scott Michelle S MS Boisvert François-Michel FM McDowall Mark D MD Lamond Angus I AI Barton Geoffrey J GJ
Nucleic acids research 20100726 21
Although the nucleolar localization of proteins is often believed to be mediated primarily by non-specific retention to core nucleolar components, many examples of short nucleolar targeting sequences have been reported in recent years. In this article, 46 human nucleolar localization sequences (NoLSs) were collated from the literature and subjected to statistical analysis. Of the residues in these NoLSs 48% are basic, whereas 99% of the residues are predicted to be solvent-accessible with 42% in ...[more]