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N-{2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]eth-yl}pyridin-2-amine monohydrate.

ABSTRACT: In the title compound, C(18)H(24)N(4)O·H(2)O, the piperizine ring adopts a chair conformation and the dihedral angle between the phenyl and pyridine rings is 39.9?(3)°. The comformations of the attachment of the anisole and N-ethyl-pyridin-2-amine groups to the piperazine ring are +anti-periplanar. An intra-molecular C-H?O inter-action occurs. In the crystal, the water mol-ecule links the mol-ecules into chains through O-H?N hydrogen bonds. Weak N-H?O, C-H?N and C-H?O inter-actions further stabilize the crystal structure.

SUBMITTER: Jiang QF

PROVIDER: S-EPMC3006790 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature

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N-{2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]eth-yl}pyridin-2-amine monohydrate.

Jiang Quan-Fu QF Lu Chun-Xiong CX

Acta crystallographica. Section E, Structure reports online 20100623 Pt 7

In the title compound, C(18)H(24)N(4)O·H(2)O, the piperizine ring adopts a chair conformation and the dihedral angle between the phenyl and pyridine rings is 39.9 (3)°. The comformations of the attachment of the anisole and N-ethyl-pyridin-2-amine groups to the piperazine ring are +anti-periplanar. An intra-molecular C-H⋯O inter-action occurs. In the crystal, the water mol-ecule links the mol-ecules into chains through O-H⋯N hydrogen bonds. Weak N-H⋯O, C-H⋯N and C-H⋯O inter-actions further stabi ...[more]

PMID: 21587944

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