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2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide.

ABSTRACT: In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6?(9)°. The conformations of the attachment of the anisole and N-ethyl-pyridin-2-amine groups to the piperazine ring are (+)anti-periplanar. Intra-molecular C-H?O and N-H?N inter-actions occur. In the crystal, inter-molecular C-H?N hydrogen bonds are present. There are two crystallographically independent but identical mol-ecules per asymmetric unit.

SUBMITTER: Lu C

PROVIDER: S-EPMC3050313 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature

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2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide.

Lu Chunxiong C Jiang Quanfu Q

Acta crystallographica. Section E, Structure reports online 20101224 Pt 1

In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethyl-pyridin-2-amine groups to the piperazine ring are (+)anti-periplanar. Intra-molecular C-H⋯O and N-H⋯N inter-actions occur. In the crystal, inter-molecular C-H⋯N hydrogen bonds are present. There are two crystallographically independent but identical mol-ecules per asymm ...[more]

PMID: 21522722

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