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(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon-yl}-2-oxo-1,3-oxazolidine-3-carboxamide.

ABSTRACT: The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl-ene carbon flap atoms deviating by 0.428?(1) and 0.364?(2)?Å from the best least-square planes formed by the four other ring atoms. An intra-molecular N-H?O hydrogen bond contributes to the folded conformation of the mol-ecule. In the crystal, weak inter-molecular C-H?O inter-actions connect the mol-ecules into helices along the the twofold screw axes.

SUBMITTER: Berredjem M

PROVIDER: S-EPMC3007004 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature

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(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon-yl}-2-oxo-1,3-oxazolidine-3-carboxamide.

Berredjem Malika M Allaoui Assia A Direm Amani A Aouf Noureddine N Benali-Cherif Nourredine N

Acta crystallographica. Section E, Structure reports online 20100609 Pt 7

The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl-ene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-square planes formed by the four other ring atoms. An intra-molecular N-H⋯O hydrogen bond contributes to the ...[more]

PMID: 21587844

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