Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

1-(2-Azido-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.

ABSTRACT: In the title compound, C(20)H(20)N(4)O(2), the piperidine ring adopts a distorted boat conformation. The two phenyl rings form dihedral angles of 82.87?(1) and 84.40?(1)° with respect to the piperidine ring. The crystal packing is stabilized by inter-molecular C-H?O and C-H?N inter-actions.

SUBMITTER: Yuvaraj H

PROVIDER: S-EPMC3009351 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

1-(2-Azido-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.

Yuvaraj Haldorai H Sundaramoorthy S S Velmurugan D D Kalkhambkar Rajesh G RG

Acta crystallographica. Section E, Structure reports online 20101009 Pt 11

In the title compound, C(20)H(20)N(4)O(2), the piperidine ring adopts a distorted boat conformation. The two phenyl rings form dihedral angles of 82.87 (1) and 84.40 (1)° with respect to the piperidine ring. The crystal packing is stabilized by inter-molecular C-H⋯O and C-H⋯N inter-actions. ...[more]

PMID: 21588942

Similar Datasets

1-(2-Bromo-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.

Project description:In the title compound, C(20)H(20)BrNO(2), the piperidone ring adopts a boat conformation. The phenyl rings are oriented at dihedral angles of 97.8?(2) and 96.0?(1)° with respect to the best plane through the piperidine ring. The dihedral angle between the two phenyl rings is 49.7?(1)°. In the crystal, bifurcated C-H?O hydrogen bonds form a R(2) (1)(7) ring motif, linking the mol-ecules into centrosymmetric dimers.

| S-EPMC2979607 | biostudies-literature

1-(2-Chloro-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.

Project description:The asymmetric unit of the title compound, C(20)H(20)ClNO(2), contains two crystallographically independent mol-ecules of similar geometry. The piperidine ring adopts a distorted boat conformation in both mol-ecules, in which the N atom assumes an almost planar configuration.

| S-EPMC2971901 | biostudies-other

Crystal structure of 1-(2-chloro-acet-yl)-2,6-bis-(4-fluoro-phen-yl)-3,3-di-methyl-piperidin-4-one.

Project description:In the title mol-ecule, C21H20ClF2NO2, the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43?(1)°. A weak intra-molecular C-H?? inter-action is observed. In the crystal, weak C-H?O hydrogen bonds and weak C-H?? inter-actions connect the mol-ecules, forming a three-dimensional network.

| S-EPMC4257194 | biostudies-literature

2,6-Diphenyl-3-(prop-2-en-1-yl)piperidin-4-one.

Project description:In the title compound, C20H21NO, the dihedral angle between the phenyl ring is 47.5 (1)° and the piperidine ring adopts a chair conformation. In the crystal, mol-ecules are linked by C-H⋯π inter-actions into dimers with the mol-ecules related by twofold symmetry.

| S-EPMC9462206 | biostudies-literature

3-Isopropyl-1-{2-[(1-methyl-1H-tetra-zol-5-yl)sulfan-yl]acet-yl}-2,6-di-phenyl-piperidin-4-one hemihydrate.

Project description:In the title compound, C24H27N5O2S·0.5H2O, the piperidine ring adopts a distorted boat conformation. The phenyl rings subtend dihedral angles of 69.7?(1) and 88.7?(1)° with the best plane through the piperidine moiety. In the crystal, symmetry-related mol-ecules are linked through a network of C-H?O and C-H?N inter-actions, the former connecting them into zigzag chains along the c-axis direction and the latter forming an R (2) 2(4)motif. The dimer formation (C-H?N) and the repetition of symmetry-related molecules (C-H?O) along the b-axis direction stabilize the packing mode. The water mol-ecule is located on a twofold rotation axis.

| S-EPMC3884276 | biostudies-literature

1-(2,2-Di-chloro-acet-yl)-3-ethyl-2,6-di-phenyl-piperidin-4-one.

Project description:The asymmetric unit of the title compound, C21H21Cl2NO2, contains two independent mol-ecules that show similar geometrical features. The piperidine ring adopts a distorted boat conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring are oriented at angles of 65.4 (1) [64.7 (2)°] and 89.2 (1)° [86.3 (2)°] with respect to the least-squares plane of the piperidine ring. In the crystal, adjacent mol-ecules are linked by a network of C-H⋯O inter-actions, forming a C(6) chain along the c-axis direction.

| S-EPMC3648321 | biostudies-literature

[(4E)-1-Methyl-2,6-diphenyl-3-(propan-2-yl)piperidin-4-yl-idene]amino 3-methyl-benzoate.

Project description:In the title compound, C29H32N2O2, the piperidine ring exists in a chair conformation (the bond-angle sum at the sp (2)-hybridized C atom is 359.79°). The phenyl rings and the methyl group substituted on the heterocyclic ring are in equatorial orientations. In the crystal, pairs of C-H?? inter-actions result in the formation of inversion dimers.

| S-EPMC3793771 | biostudies-literature

2,6-Bis(3-methoxy-phen-yl)-3-methyl-piperidin-4-one.

Project description:In the mol-ecule of the title compound, C(20)H(23)NO(3), the bulky methoxy-phenyl substituents at the equatorial 2,6-positions crowd the vicinity of the equatorial amino H atom and prevent it from forming inter-molecular hydrogen bonds. The piperidine ring adopts a distorted chair conformation.

| S-EPMC2972106 | biostudies-literature

Ethyl 4-hy-droxy-2,6-diphenyl-1-[2-(piperidin-1-yl)acet-yl]-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate.

Project description:In the title compound, C(27)H(32)N(2)O(4), the piperidine and tetra-hydro-pyridine rings adopt chair and half-chair conformations, respectively. The dihedral angle between the two phenyl rings is 32.9?(1)°. The mol-ecular structure is stabilized by a strong intra-molecular O-H?O hydrogen bond, generating an S(6) motif. In the crystal, inter-molecular C-H?O inter-actions form a ribbon-like structure along the a axis.

| S-EPMC3007457 | biostudies-literature

Crystal structure of 1-(2-chloro-acet-yl)-3,3-dimethyl-2,6-di-p-tolyl-piperidin-4-one.

Project description:In the title compound, C23H26ClNO2, the piperidin-4-one ring adopts a distorted boat conformation. The two p-tolyl rings are nearly normal to each other, making a dihedral angle of 83.33 (10)°. They are inclined to the mean plane of the piperidine ring by 73.2 (1) and 87.22 (9)°. In the crystal, there are no significant inter-molecular inter-actions present.

| S-EPMC4350729 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data