Ontology highlight
ABSTRACT:
SUBMITTER: Feehally J
PROVIDER: S-EPMC3013538 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Feehally John J Farrall Martin M Boland Anne A Gale Daniel P DP Gut Ivo I Heath Simon S Kumar Ashish A Peden John F JF Maxwell Patrick H PH Morris David L DL Padmanabhan Sandosh S Vyse Timothy J TJ Zawadzka Anna A Rees Andrew J AJ Lathrop Mark M Ratcliffe Peter J PJ
Journal of the American Society of Nephrology : JASN 20100701 10
Demographic and family studies support the existence of a genetic contribution to the pathogenesis of IgA nephropathy, but results from genetic association studies of candidate genes are inconsistent. To systematically survey common genetic variation in this disease, we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected from the UK Glomerulonephritis DNA Bank. We used two groups of controls: parents of affected individuals and previously genotyped, unaffected, ...[more]