Ontology highlight
ABSTRACT:
SUBMITTER: Zhou XJ
PROVIDER: S-EPMC4014895 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Zhou Xu-Jie XJ Qi Yuan-Yuan YY Hou Ping P Lv Ji-Cheng JC Shi Su-Fang SF Liu Li-Jun LJ Zhao Na N Zhang Hong H
Scientific reports 20140509
The effect of genetic markers associated with IgA nephropathy on risk of disease in sub-phenotype and progression is uncertain. Data from 2096 Chinese patients were used to create both un-weighted (uw) and weighted (w) genetic risk score (GRS). The association between GRS with disease susceptibility and clinical parameters were assessed. All nine selected single nucleotide polymorphisms (SNPs) were associated with susceptibility to IgAN. uwGRS and wGRS showed a similar fit in disease association ...[more]