Histone demethylation and timely DNA replication.
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ABSTRACT:
SUBMITTER: Gerace EL
PROVIDER: S-EPMC3016942 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
Histone demethylation and timely DNA replication.
Gerace Erica L EL Moazed Danesh D
Molecular cell 20101201 5
It is well-established that silent regions of the genome replicate late during S phase. In this issue of Molecular Cell, Black et al. (2010) uncover a conserved role for the JMJD2 family of histone demethylases in promoting replication within silent chromatin regions that contain histone H3 lysine 9 methylation and HP1. ...[more]
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