Ontology highlight
ABSTRACT:
SUBMITTER: Forrester MT
PROVIDER: S-EPMC3023561 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Journal of lipid research 20101102 2
Protein S-acylation is a major posttranslational modification whereby a cysteine thiol is converted to a thioester. A prototype is S-palmitoylation (fatty acylation), in which a protein undergoes acylation with a hydrophobic 16 carbon lipid chain. Although this modification is a well-recognized determinant of protein function and localization, current techniques to study cellular S-acylation are cumbersome and/or technically demanding. We recently described a simple and robust methodology to rap ...[more]