Ontology highlight
ABSTRACT:
SUBMITTER: Sonnenberg GF
PROVIDER: S-EPMC3035987 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Sonnenberg Gregory F GF Monticelli Laurel A LA Elloso M Merle MM Fouser Lynette A LA Artis David D
Immunity 20101230 1
Fetal CD4(+) lymphoid tissue inducer (LTi) cells play a critical role in the development of lymphoid tissues. Recent studies identified that LTi cells persist in adults and are related to a heterogeneous population of innate lymphoid cells that have been implicated in inflammatory responses. However, whether LTi cells contribute to protective immunity remains poorly defined. We demonstrate that after infection with Citrobacter rodentium, CD4(+) LTi cells were a dominant source of interleukin-22 ...[more]