The role of the microenvironment in tumor immune surveillance.
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ABSTRACT:
SUBMITTER: Oluwadara O
PROVIDER: S-EPMC3043348 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Publications
The role of the microenvironment in tumor immune surveillance.
Oluwadara Oluwadayo O Giacomelli Luca L Brant Xenia X Christensen Russell R Avezova Raisa R Kossan George G Chiappelli Francesco F
Bioinformation 20110106 7
The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O'Shea & Paul, 2010 [4]). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions. ...[more]
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