Nitric oxide-releasing electrospun polymer microfibers.
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ABSTRACT:
SUBMITTER: Coneski PN
PROVIDER: S-EPMC3045468 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Publications
Nitric oxide-releasing electrospun polymer microfibers.
Coneski Peter N PN Nash Jessica A JA Schoenfisch Mark H MH
ACS applied materials & interfaces 20110120 2
The preparation of electrospun polymer microfibers with nitric oxide (NO)-release capabilities is described. Polymer solutions containing disodium 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), a low-molecular-weight NO donor, were electrospun to generate fibers ranging from 100-3000 nm in diameter capable of releasing NO upon immersion in aqueous solutions under physiological conditions (pH 7.4, 37 °C), with kinetics depending on polymer composition and fiber diameter. T ...[more]
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