Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhary S
PROVIDER: S-EPMC3050508 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Tetrahedron 20110101 3
Representatives of the C-homoaporphine class of alkaloids have shown interesting biological activities. To date the synthesis of these molecules has never been attempted via a direct arylation strategy. We report herein the first Pd-mediated intramolecular direct arylation in the synthesis of C-homoaporphines via the use of microwaves. Use of tricyclohexylphosphine tetrafluoroborate as ligand gave good percentage conversions and suppressed competing debromination with the substrates evaluated. T ...[more]