Ontology highlight
ABSTRACT:
SUBMITTER: Zorzini V
PROVIDER: S-EPMC3053169 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Zorzini Valentina V Haesaerts Sarah S Donegan Niles P NP Fu Zhibiao Z Cheung Ambrose L AL van Nuland Nico A J NA Loris Remy R
Acta crystallographica. Section F, Structural biology and crystallization communications 20110225 Pt 3
mazEF modules encode toxin-antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin-antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P2(1)2(1)2(1). The crystals diffracted to 2.1 Å resolution and are likely to contain two SaMazF dim ...[more]