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Practical synthesis of PC190723, an inhibitor of the bacterial cell division protein FtsZ.

ABSTRACT: A high-yielding and practical synthesis of the bacterial cell division inhibitor PC190723 is described. The synthesis is completed in a longest linear sequence of five steps from commercially available starting materials and can be readily executed on a multigram scale.

SUBMITTER: Sorto NA 

PROVIDER: S-EPMC3068231 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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Practical synthesis of PC190723, an inhibitor of the bacterial cell division protein FtsZ.

Sorto Nohemy A NA   Olmstead Marilyn M MM   Shaw Jared T JT  

The Journal of organic chemistry 20101029 22

A high-yielding and practical synthesis of the bacterial cell division inhibitor PC190723 is described. The synthesis is completed in a longest linear sequence of five steps from commercially available starting materials and can be readily executed on a multigram scale. ...[more]

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