Ontology highlight
ABSTRACT:
SUBMITTER: Puel A
PROVIDER: S-EPMC3070042 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20110224 6025
Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent infections of the skin, nails, and oral and genital mucosae caused by Candida albicans and, to a lesser extent, Staphylococcus aureus, in patients with no other infectious or autoimmune manifestations. We report two genetic etiologies of CMCD: autosomal recessive deficiency in the cytokine receptor, interleukin-17 receptor A (IL-17RA), and autosomal dominant deficiency of the cytokine interleukin-17F (IL ...[more]