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Biomimetic glass nanopores employing aptamer gates responsive to a small molecule.

ABSTRACT: We report the preparation of 20 and 65 nm radii glass nanopores whose surface is modified with DNA aptamers controlling the molecular transport through the nanopores in response to small molecule binding.

SUBMITTER: Abelow AE 

PROVIDER: S-EPMC3073859 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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Biomimetic glass nanopores employing aptamer gates responsive to a small molecule.

Abelow Alexis E AE   Schepelina Olga O   White Ryan J RJ   Vallée-Bélisle Alexis A   Plaxco Kevin W KW   Zharov Ilya I  

Chemical communications (Cambridge, England) 20100923 42

We report the preparation of 20 and 65 nm radii glass nanopores whose surface is modified with DNA aptamers controlling the molecular transport through the nanopores in response to small molecule binding. ...[more]

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