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Open vessel mode microwave-assisted synthesis of 2-oxazolines from carboxylic acids.


ABSTRACT: Microwave-assisted synthesis of 2-oxazolines from carboxylic acids using the open vessel technique is described. This efficient method involves direct condensation of carboxylic acids with excess 2-amino-2-methyl-1-propanol at 170 °C to give the corresponding 2-oxazolines in moderate to excellent yields.

SUBMITTER: Sharma R 

PROVIDER: S-EPMC3083025 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature

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Open vessel mode microwave-assisted synthesis of 2-oxazolines from carboxylic acids.

Sharma Rishi R   Vadivel Subramanian K SK   Duclos Richard I RI   Makriyannis Alexandros A  

Tetrahedron letters 20091001 42


Microwave-assisted synthesis of 2-oxazolines from carboxylic acids using the open vessel technique is described. This efficient method involves direct condensation of carboxylic acids with excess 2-amino-2-methyl-1-propanol at 170 °C to give the corresponding 2-oxazolines in moderate to excellent yields. ...[more]

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