Ontology highlight
ABSTRACT:
SUBMITTER: Harvey BK
PROVIDER: S-EPMC3084899 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Harvey Brandon K BK Richie Christopher T CT Hoffer Barry J BJ Airavaara Mikko M
Journal of neural transmission (Vienna, Austria : 1996) 20101008 1
The identification of genes linked to neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD) and Parkinson's disease (PD) has led to the development of animal models for studying mechanism and evaluating potential therapies. None of the transgenic models developed based on disease-associated genes have been able to fully recapitulate the behavioral and pathological features of the corresponding disease. However, there has been ...[more]