Ontology highlight
ABSTRACT:
SUBMITTER: Sharpe S
PROVIDER: S-EPMC3089984 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Sharpe Simon S Simonetti Karen K Yau Jason J Walsh Patrick P
Biomacromolecules 20110401 5
The characterization of the molecular structure and physical properties of self-assembling peptides is an important aspect of optimizing their utility as scaffolds for biomaterials and other applications. Here we report the formation of autofluorescent fibrils by an octapeptide (GVGVAGVG) derived via a single amino acid substitution in one of the hydrophobic repeat elements of human elastin. This is the shortest and most well-defined peptide so far reported to exhibit intrinsic fluorescence in t ...[more]