Ontology highlight
ABSTRACT:
SUBMITTER: Pyzik M
PROVIDER: S-EPMC3092355 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Pyzik Michał M Charbonneau Benoit B Gendron-Pontbriand Eve-Marie EM Babić Marina M Krmpotić Astrid A Jonjić Stipan S Vidal Silvia M SM
The Journal of experimental medicine 20110425 5
Recognition of mouse cytomegalovirus (MCMV)-infected cells by activating NK cell receptors was first described in the context of Ly49H, which confers resistance to C57BL/6 mice. We investigated the ability of other activating Ly49 receptors to recognize MCMV-infected cells in mice from various H-2 backgrounds. We observed that Ly49P1 from NOD/Ltj mice, Ly49L from BALB mice, and Ly49D2 from PWK/Pas mice respond to MCMV-infected cells in the context of H-2D(k) and the viral protein m04/gp34. Recog ...[more]