Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez RM
PROVIDER: S-EPMC3097095 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Gonzalez Rachel M RM Zhang Qibin Q Zangar Richard C RC Smith Richard D RD Metz Thomas O TO
Analytical biochemistry 20110301 1
We have developed a fibrinogen-specific sandwich enzyme-linked immunosorbent assay (ELISA) microarray assay for use in qualitatively distinguishing between blood plasma and serum samples. Three capture antibodies (49D2, HPA001900, and F8512) were evaluated in conjunction with 1D6 as the detection antibody. The data show that 49D2 and (to a lesser extent) F8512 successfully identify previously unknown plasma and serum samples based on approximately a 28-fold difference in signal intensity between ...[more]