Ontology highlight
ABSTRACT:
SUBMITTER: Zheng W
PROVIDER: S-EPMC3103939 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Zheng Wenhua W Zhang Zuhui Z Kaplan Matthew J MJ Antilla Jon C JC
Journal of the American Chemical Society 20110222 10
We disclose a novel high yielding and highly enantioselective chiral calcium VAPOL phosphate-catalyzed chlorination of 3-substituted oxindoles with N-chlorosuccinimide (NCS). The reaction conditions are also shown to be effective for the catalytic enantioselective Michael addition of 3-aryloxindoles to methyl vinyl ketone. ...[more]