Ontology highlight
ABSTRACT:
SUBMITTER: Carrai M
PROVIDER: S-EPMC3107225 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Carrai Maura M Steinke Verena V Vodicka Pavel P Pardini Barbara B Rahner Nils N Holinski-Feder Elke E Morak Monika M Schackert Hans K HK Görgens Heike H Stemmler Susanne S Betz Beate B Kloor Matthias M Engel Christoph C Büttner Reinhard R Naccarati Alessio A Vodickova Ludmila L Novotny Jan J Stein Angelika A Hemminki Kari K Propping Peter P Försti Asta A Canzian Federico F Barale Roberto R Campa Daniele D
PloS one 20110602 6
Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the subsequent efficiency of avoiding and/or eliminating possible threats to the organism. By using a tagging approach in the region of Taste Receptor 2R38 (TAS2R38) gene, we investigated all the common genetic variation of this gene region in relati ...[more]