Ontology highlight
ABSTRACT:
SUBMITTER: Szczesny P
PROVIDER: S-EPMC3110756 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Szczesny Pawel P Iacovache Ioan I Muszewska Anna A Ginalski Krzysztof K van der Goot F Gisou FG Grynberg Marcin M
PloS one 20110608 6
A number of bacterial virulence factors have been observed to adopt structures similar to that of aerolysin, the principal toxin of Aeromonas species. However, a comprehensive description of architecture and structure of the aerolysin-like superfamily has not been determined. In this study, we define a more compact aerolysin-like domain--or aerolysin fold--and show that this domain is far more widely spread than anticipated since it can be found throughout kingdoms. The aerolysin-fold could be f ...[more]