Ontology highlight
ABSTRACT:
SUBMITTER: Jia L
PROVIDER: S-EPMC3113768 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Jia Liwei L Liu Fengming F Hansen Steen H SH Ter Beest Martin B A MB Zegers Mirjam M P MM
Molecular biology of the cell 20110420 12
Classic cadherins are important regulators of tissue morphogenesis. The predominant cadherin in epithelial cells, E-cadherin, has been extensively studied because of its critical role in normal epithelial development and carcinogenesis. Epithelial cells may also coexpress other cadherins, but their roles are less clear. The Madin Darby canine kidney (MDCK) cell line has been a popular mammalian model to investigate the role of E-cadherin in epithelial polarization and tubulogenesis. However, MDC ...[more]