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Virus-PEDOT nanowires for biosensing.

ABSTRACT: The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.

SUBMITTER: Arter JA

PROVIDER: S-EPMC3116991 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature

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Virus-PEDOT nanowires for biosensing.

Arter Jessica A JA Taggart David K DK McIntire Theresa M TM Penner Reginald M RM Weiss Gregory A GA

Nano letters 20101101 12

The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowi ...[more]

PMID: 21038915

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