Ontology highlight
ABSTRACT:
SUBMITTER: Dumitrescu L
PROVIDER: S-EPMC3128106 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Dumitrescu Logan L Carty Cara L CL Taylor Kira K Schumacher Fredrick R FR Hindorff Lucia A LA Ambite José L JL Anderson Garnet G Best Lyle G LG Brown-Gentry Kristin K Bůžková Petra P Carlson Christopher S CS Cochran Barbara B Cole Shelley A SA Devereux Richard B RB Duggan Dave D Eaton Charles B CB Fornage Myriam M Franceschini Nora N Haessler Jeff J Howard Barbara V BV Johnson Karen C KC Laston Sandra S Kolonel Laurence N LN Lee Elisa T ET MacCluer Jean W JW Manolio Teri A TA Pendergrass Sarah A SA Quibrera Miguel M Shohet Ralph V RV Wilkens Lynne R LR Haiman Christopher A CA Le Marchand Loïc L Buyske Steven S Kooperberg Charles C North Kari E KE Crawford Dana C DC
PLoS genetics 20110630 6
For the past five years, genome-wide association studies (GWAS) have identified hundreds of common variants associated with human diseases and traits, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels. Approximately 95 loci associated with lipid levels have been identified primarily among populations of European ancestry. The Population Architecture using Genomics and Epidemiology (PAGE) study was established in 2008 ...[more]