Ontology highlight
ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC7145272 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Hu Yao Y Graff Mariaelisa M Haessler Jeffrey J Buyske Steven S Bien Stephanie A SA Tao Ran R Highland Heather M HM Nishimura Katherine K KK Zubair Niha N Lu Yingchang Y Verbanck Marie M Hilliard Austin T AT Klarin Derek D Damrauer Scott M SM Ho Yuk-Lam YL Wilson Peter W F PWF Chang Kyong-Mi KM Tsao Philip S PS Cho Kelly K O'Donnell Christopher J CJ Assimes Themistocles L TL Petty Lauren E LE Below Jennifer E JE Dikilitas Ozan O Schaid Daniel J DJ Kosel Matthew L ML Kullo Iftikhar J IJ Rasmussen-Torvik Laura J LJ Jarvik Gail P GP Feng Qiping Q Wei Wei-Qi WQ Larson Eric B EB Mentch Frank D FD Almoguera Berta B Sleiman Patrick M PM Raffield Laura M LM Correa Adolfo A Martin Lisa W LW Daviglus Martha M Matise Tara C TC Ambite Jose Luis JL Carlson Christopher S CS Do Ron R Loos Ruth J F RJF Wilkens Lynne R LR Le Marchand Loic L Haiman Chris C Stram Daniel O DO Hindorff Lucia A LA North Kari E KE Kooperberg Charles C Cheng Iona I Peters Ulrike U
PLoS genetics 20200330 3
Lipid levels are important markers for the development of cardio-metabolic diseases. Although hundreds of associated loci have been identified through genetic association studies, the contribution of genetic factors to variation in lipids is not fully understood, particularly in U.S. minority groups. We performed genome-wide association analyses for four lipid traits in over 45,000 ancestrally diverse participants from the Population Architecture using Genomics and Epidemiology (PAGE) Study, fol ...[more]