Ontology highlight
ABSTRACT:
SUBMITTER: Haiman CA
PROVIDER: S-EPMC3357304 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Haiman Christopher A CA Fesinmeyer Megan D MD Spencer Kylee L KL Buzková Petra P Voruganti V Saroja VS Wan Peggy P Haessler Jeff J Franceschini Nora N Monroe Kristine R KR Howard Barbara V BV Jackson Rebecca D RD Florez Jose C JC Kolonel Laurence N LN Buyske Steven S Goodloe Robert J RJ Liu Simin S Manson Joann E JE Meigs James B JB Waters Kevin K Mukamal Kenneth J KJ Pendergrass Sarah A SA Shrader Peter P Wilkens Lynne R LR Hindorff Lucia A LA Ambite Jose Luis JL North Kari E KE Peters Ulrike U Crawford Dana C DC Le Marchand Loic L Pankow James S JS
Diabetes 20120403 6
Common genetic risk variants for type 2 diabetes (T2D) have primarily been identified in populations of European and Asian ancestry. We tested whether the direction of association with 20 T2D risk variants generalizes across six major racial/ethnic groups in the U.S. as part of the Population Architecture using Genomics and Epidemiology Consortium (16,235 diabetes case and 46,122 control subjects of European American, African American, Hispanic, East Asian, American Indian, and Native Hawaiian a ...[more]