Multipotent capacity of immortalized human bronchial epithelial cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Delgado O
PROVIDER: S-EPMC3131301 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Multipotent capacity of immortalized human bronchial epithelial cells.
Delgado Oliver O Kaisani Aadil A AA Spinola Monica M Xie Xian-Jin XJ Batten Kimberly G KG Minna John D JD Wright Woodring E WE Shay Jerry W JW
PloS one 20110707 7
While the adult murine lung utilizes multiple compartmentally restricted progenitor cells during homeostasis and repair, much less is known about the progenitor cells from the human lung. Translating the murine stem cell model to humans is hindered by anatomical differences between species. Here we show that human bronchial epithelial cells (HBECs) display characteristics of multipotent stem cells of the lung. These HBECs express markers indicative of several epithelial types of the adult lung w ...[more]
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