Ontology highlight
ABSTRACT:
SUBMITTER: Rozmus J
PROVIDER: S-EPMC3132532 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Rozmus Jacob J Schultz Kirk R KR
Expert review of hematology 20110601 3
Chronic graft-versus-host disease (cGVHD ) is a leading cause of allogeneic hematopoietic stem-cell transplantation-related mortality and morbidity. It is an immune-mediated disorder that can target almost any organ in the body, often with devastating consequences. The immune-suppressive medications currently used to treat it are equally toxic and are often not very effective. At this time, our understanding of its pathophysiology is limited. The discovery of potential biomarkers offers new poss ...[more]