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Highly efficient gold(I)-catalyzed Overman rearrangement in water.

ABSTRACT: A highly efficient gold(I)-catalyzed Overman rearrangement of allylic trichloroacetimidates to allylic trichloroacetamides in water is reported. With this environmentally benign and scalable protocol, a series of C3-alkyl substituted allylic trichloroacetamides were synthesized in good to high yields.

SUBMITTER: Xing D

PROVIDER: S-EPMC3135174 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Highly efficient gold(I)-catalyzed Overman rearrangement in water.

Xing Dong D Yang Dan D

Beilstein journal of organic chemistry 20110608

A highly efficient gold(I)-catalyzed Overman rearrangement of allylic trichloroacetimidates to allylic trichloroacetamides in water is reported. With this environmentally benign and scalable protocol, a series of C3-alkyl substituted allylic trichloroacetamides were synthesized in good to high yields. ...[more]

PMID: 21804872

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