Ontology highlight
ABSTRACT:
SUBMITTER: van Manen D
PROVIDER: S-EPMC3141012 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
van Manen Daniëlle D Delaneau Olivier O Kootstra Neeltje A NA Boeser-Nunnink Brigitte D BD Limou Sophie S Bol Sebastiaan M SM Burger Judith A JA Zwinderman Aeilko H AH Moerland Perry D PD van 't Slot Ruben R Zagury Jean-François JF van 't Wout Angélique B AB Schuitemaker Hanneke H
PloS one 20110721 7
<h4>Background</h4>AIDS develops typically after 7-11 years of untreated HIV-1 infection, with extremes of very rapid disease progression (<2 years) and long-term non-progression (>15 years). To reveal additional host genetic factors that may impact on the clinical course of HIV-1 infection, we designed a genome-wide association study (GWAS) in 404 participants of the Amsterdam Cohort Studies on HIV-1 infection and AIDS.<h4>Methods</h4>The association of SNP genotypes with the clinical course of ...[more]