Ontology highlight
ABSTRACT:
SUBMITTER: Lee BK
PROVIDER: S-EPMC3148836 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Tetrahedron letters 20090701 26
Simple and efficient procedures for the Pd-catalyzed cross-coupling reaction of aryl chlorides and dimethylamine are described. At room temperature with a strong base, t-BuXPhos is employed as the supporting ligand; at 110 °C with a weak base, XPhos is employed as the supporting ligand. In each of these cases, commercially available solutions constitute the source of the dimethylamine, and recently disclosed precatalysts constitute the source of the ligand and Pd. This work further expands the u ...[more]