Ontology highlight
ABSTRACT:
SUBMITTER: Veit G
PROVIDER: S-EPMC3149370 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20110607 31
Cellular receptors for collagens belong to the family of β(1) integrins. In the epidermis, integrin α(2)β(1) is the only collagen-binding integrin present. Its expression is restricted to basal keratinocytes with uniform distribution on the cell surface of those cells. Although α(2)β(1) receptors localized at the basal surface interact with basement membrane proteins collagen IV and laminin 111 and 332, no interaction partners have been reported for these integrin molecules at the lateral and ap ...[more]