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[(2S,5R)-1-Methyl-5-phenyl-pyrrolidin-2-yl]diphenyl-methanol.

ABSTRACT: In the title compound, C(24)H(25)NO, the phenyl and diphenyl-methanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hy-droxy group forms an intra-molecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the mol-ecule. The crystal packing features C-H?? inter-actions. Two slightly displaced co-planar orientations were found for one of the phenyl rings; the major component had a site-occupancy factor of 0.782?(15).

SUBMITTER: Zukerman-Schpector J

PROVIDER: S-EPMC3151780 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

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[(2S,5R)-1-Methyl-5-phenyl-pyrrolidin-2-yl]diphenyl-methanol.

Zukerman-Schpector Julio J Venturini Moro Angélica A Lüdtke Diogo S DS Correia Carlos Roque D CR Tiekink Edward R T ER

Acta crystallographica. Section E, Structure reports online 20110625 Pt 7

In the title compound, C(24)H(25)NO, the phenyl and diphenyl-methanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hy-droxy group forms an intra-molecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the mol-ecule. The crystal packing features C-H⋯π inter-actions. Two slightly displaced co-planar orientations were found for one of the phenyl ring ...[more]

PMID: 21837179

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