Ontology highlight
ABSTRACT:
SUBMITTER: Wang R
PROVIDER: S-EPMC3154685 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20110201 2
The CRISPRs (Clustered Regularly Interspaced Short Palindromic Repeats) found in prokaryotic genomes confer small RNA-mediated protection against viruses and other invaders. CRISPR loci contain iterations of a short repeat sequence alternating with small segments of varying invader-derived sequences. Distinct families of CRISPR-associated Cas proteins function to cleave within the repeat sequence of CRISPR transcripts and produce the individual invader-targeting crRNAs. Here, we report the cryst ...[more]