Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli.
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ABSTRACT:
SUBMITTER: Yuhki M
PROVIDER: S-EPMC3160358 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli.
Yuhki Munehiro M Kajitani Takashi T Mizuno Takakazu T Aoki Yuko Y Maruyama Tetsuo T
Reproductive biology and endocrinology : RB&E 20110801
Studies on the mechanisms of decidualization and endometriosis are often hampered by lack of primary endometrial cells. To facilitate in vitro studies, we established a human endometrial stromal cell line, KC02-44D, immortalized with human telomerase reverse transcriptase. Upon exposure to ovarian stimuli, KC02-44D cells showed similar cytoskeletal marker or gene expression and biochemical phenotype to primary endometrial stromal cells. KC02-44D would be useful for studies of human endometrial f ...[more]
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