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ChimeraScan: a tool for identifying chimeric transcription in sequencing data.

ABSTRACT:

Summary

Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.

Availability

http://chimerascan.googlecode.com

Contact

cmaher@dom.wustl.edu

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Iyer MK

PROVIDER: S-EPMC3187648 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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ChimeraScan: a tool for identifying chimeric transcription in sequencing data.

Iyer Matthew K MK Chinnaiyan Arul M AM Maher Christopher A CA

Bioinformatics (Oxford, England) 20110811 20

<h4>Summary</h4>Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.<h4>Availability</h4>http://chimerascan.googlecode.com<h4>Contact</h4>cmaher@dom.wustl.edu<h4>Supplementary information</h4>Supplement ...[more]

PMID: 21840877

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