Ontology highlight
ABSTRACT:
SUBMITTER: Silkov A
PROVIDER: S-EPMC3190782 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Silkov Antonina A Yoon Youngdae Y Lee Hunjoong H Gokhale Nikhil N Adu-Gyamfi Emmanuel E Stahelin Robert V RV Cho Wonhwa W Murray Diana D
The Journal of biological chemistry 20110802 39
An increasing number of cytosolic proteins are shown to interact with membrane lipids during diverse cellular processes, but computational prediction of these proteins and their membrane binding behaviors remains challenging. Here, we introduce a new combinatorial computation protocol for systematic and robust functional prediction of membrane-binding proteins through high throughput homology modeling and in-depth calculation of biophysical properties. The approach was applied to the genomic sca ...[more]