Ontology highlight
ABSTRACT:
SUBMITTER: Lucas HR
PROVIDER: S-EPMC3196632 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Lucas Heather R HR Lee Jennifer C JC
Metallomics : integrated biometal science 20110203 3
Interactions of copper and membranes with α-synuclein have been implicated in pathogenic mechanisms of Parkinson's disease, yet work examining both concurrently is scarce. We have examined the effect of copper(ii) on protein/vesicle binding and found that both the copper(ii) affinity and α-helical content are enhanced for the membrane-bound protein. ...[more]