Ontology highlight
ABSTRACT:
SUBMITTER: Murea M
PROVIDER: S-EPMC3202959 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Murea Mariana M Lu Lingyi L Ma Lijun L Hicks Pamela J PJ Divers Jasmin J McDonough Caitrin W CW Langefeld Carl D CD Bowden Donald W DW Freedman Barry I BI
American journal of nephrology 20110505 6
<h4>Background</h4>African-Americans (AAs) with diabetes have high incidence rates of end-stage renal disease (ESRD) with associated high mortality. Genetic factors modulating the risk of mortality on dialysis are poorly understood.<h4>Methods</h4>A genome-wide association study was performed in 610 AAs with type 2 diabetes (T2D) and ESRD on dialysis, using the Affymetrix 6.0 platform (868,155 SNPs). Time to death was assessed using Cox proportional hazards model adjusting for ancestry and other ...[more]