Ontology highlight
ABSTRACT:
SUBMITTER: Harvey JS
PROVIDER: S-EPMC3211083 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Harvey James S JS Simonovich Scott P SP Jamison Christopher R CR MacMillan David W C DW
Journal of the American Chemical Society 20110817 35
The enantioselective α-arylation of both lactones and acyl oxazolidones has been accomplished using a combination of diaryliodonium salts and copper catalysis. These mild catalytic conditions provide a new strategy for the enantioselective construction and retention of enolizable α-carbonyl benzylic stereocenters, a valuable synthon for the production of medicinal agents. ...[more]